Bone-2 Adhesive - repairing bone fractures in three
minutes
Chinese scientists have unveiled a
groundbreaking medical adhesive named Bone-02, capable of repairing bone
fractures in as little as three minutes, a feat that could transform orthopedic
surgery.
The project, led by Dr. Lin Xianfeng at Sir Run Run Shaw Hospital in Zhejiang Province, was inspired by oysters’ remarkable ability to cling firmly to wet, moving surfaces.
Unlike traditional metal implants, Bone-02 is bioabsorbable, gradually dissolving as the bone naturally heals, eliminating the need for a second surgery to remove hardware.
Tested successfully in over 150 patients, the adhesive has demonstrated impressive strength, safety, and rapid bonding even in blood-rich environments.
Experts believe Bone-02 could dramatically reduce surgery time, lower infection risks, and accelerate recovery, marking a major breakthrough in fracture treatment worldwide.
Bone glue inspired by oysters
The development of Bone-02 is rooted in biomimicry, taking cues from how oysters withstand waves and water currents by adhering strongly to underwater surfaces. This adhesive mimics that natural resilience, giving surgeons a powerful tool to treat fractures in blood-rich environments where traditional adhesives often fail.
Within two to three minutes of application, Bone-02 can secure broken bones with exceptional bonding force—measured at more than 400 pounds. Its quick action and durability offer surgeons greater efficiency and patients a smoother healing process.
Future applications may include dental surgery, joint repair, and battlefield medicine where speed and strength are critical for successful outcomes.
Trials inspired confidence in results
Clinical trials of Bone-02 have already
involved more than 150 patients, producing encouraging outcomes. Doctors
reported that surgeries normally requiring steel plates and screws were
completed in a fraction of the time.
Beyond speed, the adhesive demonstrated robust physical properties, including a shear strength of 0.5 MPa and compressive strength of around 10 MPa, comparable to standard implants.
Importantly, Bone-02 was well tolerated by the human body, showing no major safety concerns. These findings suggest it could eventually replace many traditional fixation methods in hospitals worldwide.
Its impact could extend to emergency medicine, where quick fracture stabilization is critical. The adhesive may also prove valuable in battlefield or disaster scenarios, where surgical resources are scarce.
Inspired shift
in fracture treatment
Bone-02’s bioabsorbable design means it
naturally dissolves within about six months, disappearing as the bone regains
strength.
This eliminates the need for a second surgery
to remove metal hardware, reducing both costs and recovery risks for patients.
Orthopedic experts see this as a potential
game-changer in fracture care, particularly in complex injuries or regions with
limited access to advanced surgical facilities.
If future trials continue to confirm its effectiveness, Bone-02 could lead to a paradigm shift in how fractures are treated faster, safer, and more human-centered than ever before.
Innovations like this highlight how nature
continues to inspire modern medicine.
Such breakthroughs remind us that healing the body can be both scientific and creative. It’s a breakthrough that sounds almost like science fiction—yet it’s already saving real patients precious healing time.
Doctors even joked that the glue could make
them feel more like “carpenters” than surgeons.
This technology promises to revolutionize
orthopedic care worldwide, improving patient outcomes and reducing healthcare
burdens dramatically.
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